Accession Number : AD0690800

Title :   TEMPERATURE DEPENDENCE OF VENOM PHOSPHOLIPASE A AND RELATED HAEMOLYSIS,

Corporate Author : ARMY AEROMEDICAL RESEARCH LAB FORT RUCKER ALA

Personal Author(s) : Schane,William P. ; Wetmur,James G. ; Wilson,Charles R.

Report Date : JUN 1969

Pagination or Media Count : 16

Abstract : Phospholipase A activity of the venom of Crotalus adamanteus was found to increase by a factor of two for every 10C. increase in temperature. A percentage of haemolysis of red cells by lysolecithin produced by phospholipase A occurred at two times lower lysolecithin concentration for every 10C. decrease in temperature. Under all conditions, percent lysis increased with decreasing the temperature in a complex reaction mixture would be expected to produce an instantaneous increase in the percentage of cells lysed. (Author)

Descriptors :   (*VENOMS, *ENZYMES), (*HEMOLYSIS, VENOMS), ERYTHROCYTES, CONCENTRATION(CHEMISTRY), IN VITRO ANALYSIS, PHOSPHOLIPIDS, TOXICITY, TEMPERATURE

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE