Accession Number : AD0690800

Title :   TEMPERATURE DEPENDENCE OF VENOM PHOSPHOLIPASE A AND RELATED HAEMOLYSIS

Corporate Author : ARMY AEROMEDICAL RESEARCH LAB FORT RUCKER AL

Personal Author(s) : Schane, William P ; Wetmur, James G ; Wilson, Charles R

PDF Url : AD0690800

Report Date : Jun 1969

Pagination or Media Count : 16

Abstract : Phospholipase A activity of the venom of Crotalus adamanteus was found to increase by a factor of two for every 10C. increase in temperature. A percentage of haemolysis of red cells by lysolecithin produced by phospholipase A occurred at two times lower lysolecithin concentration for every 10C. decrease in temperature. Under all conditions, percent lysis increased with decreasing the temperature in a complex reaction mixture would be expected to produce an instantaneous increase in the percentage of cells lysed.

Descriptors :   *ENZYMES, *HEMOLYSIS, *VENOMS, CONCENTRATION(CHEMISTRY), ERYTHROCYTES, IN VITRO ANALYSIS, PHOSPHOLIPIDS, TEMPERATURE, TOXICITY

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE