Accession Number : AD0691150

Title :   ADRENAL CORTICOSTEROIDS IN SUBMAXILLARY FLUID.

Descriptive Note : Final rept. 1 Sep 66-31 Aug 68,

Corporate Author : LOYOLA UNIV HINES ILL STRITCH SCHOOL OF MEDICINE

Personal Author(s) : Katz,Fred H. ; Shannon,Ira L.

Report Date : MAY 1969

Pagination or Media Count : 11

Abstract : The purpose of this study was to investigate the corticosteroids in submaxillary gland fluid in man. Human submaxillary fluid was collected from 2 to 4 hours after ACTH simulation, and large batches were analyzed by quantitative paper chromatography for adrenal corticosteroids. The major steroids present were cortisol and cortisone, but a small amount of tetrahydrocortisol was found in two out of the three experiments. The concentrations of cortisol and cortisone after ACTH treatment were similar to those previously found in parotid fluid. The absence of any glucuronide-conjugated steroids (the form used for renal excretion) suggests that submaxillary gland secretion of these steroids is not an excretory process. (Author)

Descriptors :   (*SALIVARY GLANDS, *CORTICOSTEROID AGENTS), ADRENAL CORTEX HORMONES, DENTISTRY, MEDICAL RESEARCH, BODY FLUIDS, ADRENOCORTICOTROPIC HORMONE, SECRETION

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE