Accession Number : AD0691411
Title : THE COMPARISON OF SURVIVAL TIMES OF MONKEYS AND RATS EXPOSED TO PULSED AND STEADY-STATE REACTOR RADIATIONS.
Descriptive Note : Scientific rept.,
Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD
Personal Author(s) : Levich,C. ; Seigneur,L. J. ; Strike,T. A. ; Hansen,J. R. , Jr. ; Schlaak,J. R.
Report Date : FEB 1969
Pagination or Media Count : 27
Abstract : Macaca mulatta monkeys and Sprague-Dawley rats were unilaterally exposed to whole-body doses of gamma-neutron radiations from a TRIGA reactor. Doses of 2075, 4150, and 12,450 rads were used in the monkey studies. Doses to the rats ranged from 9400 to 66,000 rads. The animals were exposed in two ways. The steady-state animals were irradiated at a dose rate of approximately 1000 rads/minute. The other animals were exposed to a single pulse of radiations. The pulse was about 15 milliseconds wide at half amplitude. The average dose rate under the pulse was of the order of 10 to the 6th power rads/second. At doses sufficient to cause death within 2 days the ordering of deaths was significantly different between pulsed and steady-state irradiated monkeys, with the pulsed animals preceding. The mean survival time of pulsed animals was significantly shorter than their steady-state counterparts for both species of animals. (Author)
Descriptors : (*RADIATION TOLERANCE, DOSE RATE), RADIATION DOSAGE, EXPOSURE(PHYSIOLOGY), NERVOUS SYSTEM, PATHOLOGY, STATISTICAL ANALYSIS, RATS, MONKEYS, RADIATION EFFECTS
Subject Categories : Radiobiology
Distribution Statement : APPROVED FOR PUBLIC RELEASE