Accession Number : AD0692313

Title :   METABOLIC EFFECTS OF BLOOD TRANSFUSION.

Descriptive Note : Final rept. 1 Sep 60-29 Feb 68,

Corporate Author : STANFORD UNIV CALIF

Personal Author(s) : Bunker,John P.

Report Date : AUG 1969

Pagination or Media Count : 10

Abstract : The metabolic effects of massive blood transfusion have been studied. The effects of citrate-induced hypocalcemia, elevated potassium concentrations, and metabolic acidosis have been examined individually and in combination in the experimental dog and in the isolated guinea pig atrium. Special attention has been given to the role of adrenergic mechanisms in circulatory homeostasis during massive transfusion. Chemical, electrocardiographic, and hemodynamic methods have been developed to allow on-line investigation of the special risks and ultimate routine monitoring of the circulation during massive transfusion. (Author)

Descriptors :   (*BLOOD TRANSFUSION, *METABOLISM), METABOLIC DISEASES, BLOOD, CITRATES, CALCIUM, POTASSIUM, ACIDOSIS, CITRIC ACID, ADRENAL GLANDS

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE