Accession Number : AD0694428

Title :   TRANSFORMATION OF A STATIONARY POISSON FLOW OF IMPULSES IN THE SYNAPSE OF A NERVE CELL,

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Kogan,A. B. ; Popov,I. V.

Report Date : 01 MAY 1969

Pagination or Media Count : 9

Abstract : The action of a Poisson flow of impulses on one synapse for the case of background activity is analyzed in the present study. According to the mediator theory of transmission of excitation through a synapse, each impulse arriving along the axon to the synapse is accompanied by secretion of a certain number of molecules of a chemical substance, the mediator, into the synaptic fissure. It is assumed that bundles of the mediator molecules represent uniformly distributed independent positive random values x with a distribution function H(x), and that the decomposition of the mediator is constant in time. Also, it is assumed that a local postsynaptic potential (LPSP) appears in response to each input impulse and the amplitude of the LPSP is proportional to mediator concentration in a synaptic fissure. After determining distribution function for the mediator concentration, it can be used to find the amplitude probability distributions of LPSP. (Author)

Descriptors :   (*NERVE CELLS, *NERVE IMPULSES), DISTRIBUTION FUNCTIONS, STOCHASTIC PROCESSES, CENTRAL NERVOUS SYSTEM, VOLTAGE, ELECTROPHYSIOLOGY, USSR

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE