Accession Number : AD0695822

Title :   ADAPTATION TO CHRONIC HYPERBARIC OXYGEN PRESSURES.

Descriptive Note : Final scientific rept. 1 May 66-31 Sep 69,

Corporate Author : PENNSYLVANIA STATE UNIV UNIVERSITY PARK DEPT OF ZOOLOGY

Personal Author(s) : Houlihan,Rodney T.

Report Date : 17 SEP 1969

Pagination or Media Count : 9

Abstract : The report summarizes the research on the effects of hyperbaric medicine completed at the Pennsylvania State University. The progression of this research involved studies on renal function, blood flow, adrenocortical and sympatho-adreno-medullary (SAM) activity. The blood flow alterations indicated increased adrenocortical function. The adrenocortical function reaches its highest level just prior to death from oxygen poisoning. The excretion of catecholamine indicated an altered metabolism of epinephrine. It is noted that oxygen at high pressure results in the production of adrenochrome, adrenolutin and derivatives. These compounds are highly reactive and can account for the manifestations of oxygen toxicity. (Author)

Descriptors :   (*OXYGEN, TOXICITY), PRESSURE, BLOOD CIRCULATION, KIDNEYS, ADRENAL CORTEX, METABOLISM, EPINEPHRINE, AUTONOMIC NERVOUS SYSTEM

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE