Accession Number : AD0698479

Title :   RESUSCITATION AND TREATMENT OF THE INJURED.

Descriptive Note : Annual rept. 1 Nov 68-31 Oct 69,

Corporate Author : MEDICAL UNIV OF SOUTH CAROLINA CHARLESTON

Personal Author(s) : Artz,Curtis P.

Report Date : NOV 1969

Pagination or Media Count : 39

Abstract : The first section of the report has to do with the evaluation of various regimens of replacement therapy in hemorrhagic shock. This was done in dogs by producing a standard shock model from bleeding. The animal is resuscitated with a variety of replacement solutions and then a second shock is given them 24 hours later. It is the purpose of this study to determine the animal's ability to withstand a second shock after being treated initially with a variety of replacement methods. Another aspect has to do with pulmonary manifestations of trauma. Experiments were designed to test the hypothesis that following burn injury and postperfusion lung, increased transudation of plasma from the capillary space to the interstitial fluid space and subsequently to the bronchoalveolar space resulted in destruction of pulmonary surfactant with secondary development of congestive atelectasis and respiratory distress syndrome. In bioengineering several developments occurred including an expansion of the use of the X-grid and improvement in low flow hemodialysis with the SCIRT Mark III pump. A new device, the self powered infusion pump, is in the final design stage. It is hoped that this will provide a way of infusing fluids in battlefield and other situations without the use of gravity. (Author)

Descriptors :   (*SHOCK(PATHOLOGY), THERAPY), (*BLOOD CIRCULATION, WOUNDS AND INJURIES), BLOOD CHEMISTRY, STRESS(PHYSIOLOGY), HEMORRHAGE, LABELED SUBSTANCES, BURNS(INJURIES), HEMATOLOGY, DOGS, HUMANS, LUNG, EDEMA, ARTIFICIAL RESPIRATION, HEPARIN, TABLES(DATA), TISSUES(BIOLOGY)

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE