Accession Number : AD0698887

Title :   THE INTENSITY OF THE NARCOTIC ACTION OF HYDROGEN AT HIGH PRESSURE,

Corporate Author : DEFENCE SCIENTIFIC INFORMATION SERVICE OTTAWA (ONTARIO)

Personal Author(s) : Lazarev,N. V.

Report Date : OCT 1969

Pagination or Media Count : 5

Abstract : The narcotic action of hydrogen is undoubtedly very feeble. In any case, hydrogen acts much more feebly than nitrogen. In the mouse, nitrogen produces narcosis at approximately 30-35 atmospheres. Nevertheless, narcosis had not yet occurred at 55 atmospheres pressure of a nitrogen-hydrogen mixture, of which, in round figures, 10 atm was nitrogen partial pressure and 45 atm hydrogen partial pressure. If we take it that here too the narcotic action is additive, then it follows that 45 atm of hydrogen act more weakly than the 20-25 atm of nitrogen that were lacking to bring the experiment up to the narcotic partial pressure of that gas. Consequently it may be expected that narcosis, in the mouse, will be evoked by partial pressures of hydrogen above 70-70 atm (the hydrogen thus acting less than half as strongly as nitrogen). (Author)

Descriptors :   (*HYDROGEN, TOXICITY), TOXIC TOLERANCES, RESPIRATION, NITROGEN, OXYGEN, ANESTHESIA, MICE, HIGH PRESSURE, BAROMETRIC PRESSURE

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE