Accession Number : AD0699792

Title :   TRANSPLANTATION ANTIGENS IN KERATOPLASTY. I. ISOLATION OF A SOLUBLE FRACTION WITH TRANSPLANTATION ANTIGEN ACTIVITY.

Descriptive Note : Interim rept.,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : Leibowitz,Howard M. ; Luzzio,Anthony J.

Report Date : 04 SEP 1969

Pagination or Media Count : 21

Abstract : A soluble protein fraction has been isolated from the cornea by simple aqueous extraction. This preparation possesses transplantation antigen activity as demonstrated by its ability to induce a specific sensitization resulting in the accelerated destruction of a corneal graft. The corneal antigen preparation is also capable of stimulating the production of humoral antibodies but the relationship between the transplantation immunity and the antibody response remains to be elaborated. (Author)

Descriptors :   (*EYE, *ANTIGENS + ANTIBODIES), (*CORNEA, TRANSPLANTATION), (*TRANSPLANTATION, ANTIGENS + ANTIBODIES), IMMUNITY, ANTIGEN ANTIBODY REACTIONS, SURGICAL TECHNIQUES, SENSITIVITY, RESPONSE(BIOLOGY)

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE