Accession Number : AD0699840

Title :   SURVEY OF PLANTS FOR ANTIMALARIAL ACTIVITY.

Descriptive Note : Rept. no. 2 (Final comprehensive),

Corporate Author : RHODE ISLAND UNIV KINGSTON DEPT OF PHARMACOGNOSY

Personal Author(s) : Youngken,Heber W. , Jr. ; Tashiro,John T.

Report Date : 01 JAN 1970

Pagination or Media Count : 14

Abstract : Pleicoarpa mutica, Isertia hypoleuca, Tagetes filifolia, Verbena hastata, Cephaelis tomentosa, an unknown Isertia species, 'Kinkelibia,' Polysiphonia harveyii and Rhodymenia palmata were studied chemically. In addition, there were a number of plants on which only preliminary chemical work was initiated. As a result of the chemical investigation, a number of pure compounds were submitted for testing in the antimalarial screening program. These include pleiocarpine hydrochloride, dehydrodihydroquinamine, dihydroquinamine, and two uncharacterized compounds, IH-Lf-A and VH-N-1. None of these compounds showed significant antimalarial activity. (Author)

Descriptors :   (*ANTIMALARIALS, *PLANTS(BOTANY)), CHEMICAL ANALYSIS, CHEMOTHERAPEUTIC AGENTS, ALKALOIDS, GLYCOSIDES, PHENOLS, NITROGEN HETEROCYCLIC COMPOUNDS

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE