Accession Number : AD0699840
Title : SURVEY OF PLANTS FOR ANTIMALARIAL ACTIVITY.
Descriptive Note : Rept. no. 2 (Final comprehensive),
Corporate Author : RHODE ISLAND UNIV KINGSTON DEPT OF PHARMACOGNOSY
Personal Author(s) : Youngken,Heber W. , Jr. ; Tashiro,John T.
Report Date : 01 JAN 1970
Pagination or Media Count : 14
Abstract : Pleicoarpa mutica, Isertia hypoleuca, Tagetes filifolia, Verbena hastata, Cephaelis tomentosa, an unknown Isertia species, 'Kinkelibia,' Polysiphonia harveyii and Rhodymenia palmata were studied chemically. In addition, there were a number of plants on which only preliminary chemical work was initiated. As a result of the chemical investigation, a number of pure compounds were submitted for testing in the antimalarial screening program. These include pleiocarpine hydrochloride, dehydrodihydroquinamine, dihydroquinamine, and two uncharacterized compounds, IH-Lf-A and VH-N-1. None of these compounds showed significant antimalarial activity. (Author)
Descriptors : (*ANTIMALARIALS, *PLANTS(BOTANY)), CHEMICAL ANALYSIS, CHEMOTHERAPEUTIC AGENTS, ALKALOIDS, GLYCOSIDES, PHENOLS, NITROGEN HETEROCYCLIC COMPOUNDS
Subject Categories : Pharmacology
Distribution Statement : APPROVED FOR PUBLIC RELEASE