Accession Number : AD0700378

Title :   THE COBALT-60 GAMMA-RADIOLYSIS OF REDUCED GLUTATHIONE IN DEAERATED AQUEOUS SOLUTIONS,

Corporate Author : CALGARY UNIV (ALBERTA) DEPT OF CHEMISTRY

Personal Author(s) : Lal,Manohar ; Armstrong,D. A. ; Wieser,Meta

Report Date : 27 JUN 1968

Pagination or Media Count : 7

Abstract : The major products of radiolysis of air-free aqueous solutions of the tripeptide glutathione are hydrogen, hydrogen sulfide, oxidized glutathione, and gamma-glutamylalanylglycine. The last of these results from the replacement of SH by H. There is no evidence for scission of the peptide chain, and the pH dependence and magnitudes of the product yields closely resemble those of the analogous products from cysteine solutions. The radiolytic mechanism is shown to be similar to that for cysteine. (Author)

Descriptors :   (*GLUTATHIONE, *RADIATION CHEMISTRY), GLUTAMINE, PEPTIDES, SULFIDES, GAMMA RAYS, OXIDATION, CANADA

Subject Categories : Biochemistry
      Radiation and Nuclear Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE