Accession Number : AD0701226

Title :   THE EFFECT OF HYPEROXIA AND HYPOXIA ON FREE AND BOUND GAMMA-AMINOBUTYRIC ACID IN MAMMALIAN BRAIN,

Corporate Author : DEFENCE RESEARCH ESTABLISHMENT TORONTO DOWNSVIEW (ONTARIO)

Personal Author(s) : Wood ,J. D. ; Watson ,W. J.

Report Date : 14 MAY 1969

Pagination or Media Count : 5

Abstract : In rats and guinea pigs exposed to hyperoxic conditions, the levels of both bound and free gamma-aminobutyric acid in the brain were decreased, and under hypoxic conditions both were increased. A small but significant change in the proportion of gamma-aminobutyric acid in the bound form was observed in the exposed animals. The significance of the findings is discussed. (Author)

Descriptors :   (*AMINO ACIDS, BRAIN), (*BRAIN, METABOLISM), (*HYPOXIA, AMINO ACIDS), RODENTS, EXPOSURE(PHYSIOLOGY), CHEMICAL ANALYSIS, CONCENTRATION(CHEMISTRY), FATTY ACIDS, OXYGEN, PRESSURE BREATHING, CONVULSIVE DISORDERS, IN VIVO ANALYSIS, CANADA

Subject Categories : Biochemistry
      Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE