Accession Number : AD0703646

Title :   MODE OF FISSION OF BENZENE NUCLEUS IN THE MICRO-ORGANISMS AND REGULATION OF CELL GROWTH AND DIVISION BY BENZENE DERIVATIVES.

Descriptive Note : Final rept.,

Corporate Author : OKLAHOMA STATE UNIV STILLWATER DEPT OF MICROBIOLOGY

Personal Author(s) : Durham,Norman D.

Report Date : 1970

Pagination or Media Count : 10

Abstract : A species of Flavobacterium is capable of utilizing either D-trytophan or L-tryptophan as the sole source of carbon and energy for aerobic growth. D-Tryptophan is oxidized to indolepyruvic acid and this reaction is followed by a transamination reaction with the eventual formation of L-tryptophan. The organism oxidatively degrades L-tryptophan via L-kynurenine and anthranilic acid. A number of L-amino acids will serve as a source of an amino group for the transamination reaction although L-glutamic acid and L-aspartic acid appear to be the most efficient donors. Glutamine will also function as an amino donor in this microbial system. The conversion D-tryptophan to L-tryptophan in a cell-free system can be demonstrated when an electron acceptor, such as phenazine methosulfate, is present. (Author)

Descriptors :   (*BACTERIA, TRYPTOPHAN), (*TRYPTOPHAN, METABOLISM), GROWTH(PHYSIOLOGY), CELLS(BIOLOGY), CARBON, ENERGY, AROMATIC COMPOUNDS, BENZENE, AMINO ACIDS, ENZYMES, CULTURE MEDIA, OXIDATION, INHIBITION, CHLORAMPHENICOL, ESTROGENS, BIOCHEMISTRY

Subject Categories : Biochemistry
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE