Accession Number : AD0703878

Title :   MYOPIA INDUCED BY OCULAR INSTILLATION OF PHYSOSTIGMINE.

Descriptive Note : Technical rept. Aug 68-Feb 69,

Corporate Author : EDGEWOOD ARSENAL MD

Personal Author(s) : Rengstorff,Roy H.

Report Date : APR 1970

Pagination or Media Count : 18

Abstract : An 0.5% solution of physostigmine (eserine) eye drops caused myopia up to 7.50 D 30 minutes after subjects received the drug. Visual acuity decreased down to 20/400 at drug peak. The average effect of 2 drops was greater than 1 drop. There was no consensual effect in the eye not receiving physostigmine. Requiring subjects to perform a demanding near visual task resulted in greater myopia than occurred when they were given a distant visual task. (Author)

Descriptors :   (*CHOLINESTERASE INHIBITORS, *VISUAL ACUITY), EYE, DISEASES, DRUGS, DOSAGE

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE