Accession Number : AD0709771

Title :   CYANOACRYLATE ADHESIVES IN EYE WOUNDS.

Descriptive Note : Annual rept. 1 Sep 69-1 Jun 70,

Corporate Author : RETINA FOUNDATION BOSTON MASS DEPT OF CORNEA RESEARCH

Personal Author(s) : Refojo,Miguel F.

Report Date : JUN 1970

Pagination or Media Count : 16

Abstract : The report consists of five main parts: (1) treatment of chemical burns in the cornea with a glued-on contact lens, which, by keeping from the injured stroma, the collagenolytic enzymes that are released by the epithelium prevents ulceration and perforation from occurring; (2) removal of residual adhesive from the surface of the cornea by means of acetone, which provides an alternative method to mechanical removal of any remaining adhesive that may persist in the cornea after any treatment; (3) evaluation of the rate of wound healing in the cornea under a cyanoacrylate adhesive, which confirms delaying healing in the absence of epithelium over the wound; (4) continual evaluation of available cyanoacrylate adhesives in rabbit eyes; and (5) a preliminary description is given on research on biodegradation of Beta-C14 isobutyl 2-cyanoacrylate in the eyes of experimental animals. (Author)

Descriptors :   (*EYE, *WOUNDS AND INJURIES), (*TISSUES(BIOLOGY), *ADHESIVES), (*ACRYLIC RESINS, ADHESIVES), CORNEA, BURNS(INJURIES), REMOVAL, DEGRADATION, SURGERY

Subject Categories : Medical Facilities, Equipment and Supplies
      Adhesives, Seals and Binders

Distribution Statement : APPROVED FOR PUBLIC RELEASE