Accession Number : AD0710030

Title :   THE THIN-LAYER CHROMATOGRAPHY OF THE HYDROXYINDOLE-3-CARBOXYLIC ACIDS,

Corporate Author : NATIONAL RESEARCH COUNCIL OF CANADA HALIFAX (NOVA SCOTIA) ATLANTIC REGIONAL LAB

Personal Author(s) : Marchelli,Rosangela ; Hutzinger,O. ; Heacock,R. A.

Report Date : 02 DEC 1969

Pagination or Media Count : 4

Abstract : Two of the main problems that are often encountered in the use of paper and thin-layer chromatographic procedures for the detection and identification of hydroxyindoles are the lack of suitable standard compounds and reliable data on their R(F) values. The chromatographic behaviour of all four isomeric hydroxyindoles (hydroxylated in the benzene ring) has only been studied in a relatively few cases including indole, skatole, tryptamine, tryptophan, acetyltryptophan and oxindole. The 4-, 5-, 6- and 7-hydroxyindole-3-carboxylic acids have recently all been synthesized by unambiguous routes in these laboratories and the article reports the results of some investigations into the TLC properties of this group of hydroxyindoles. (Author)

Descriptors :   (*INDOLES, *THIN LAYER CHROMATOGRAPHY), (*CARBOXYLIC ACIDS, THIN LAYER CHROMATOGRAPHY), COLORIMETRIC ANALYSIS, CANADA

Subject Categories : Physical Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE