Accession Number : AD0711200

Title :   X- AND GAMMA-RADIOLYSIS OF SOME TRYPTOPHAN DIPEPTIDES,

Corporate Author : NATIONAL RESEARCH COUNCIL OF CANADA OTTAWA (ONTARIO) DIV OF BIOLOGY

Personal Author(s) : Winchester,R. V. ; Lynn,K. R.

Report Date : 17 MAR 1970

Pagination or Media Count : 8

Abstract : Irradiation of the dipeptides tryptophyl-glycine, -alanine, -leucine, -tryptophan, -tyrosine, and -phenylalanine in aerated solution gave essentially the same products in each case. The major products are those known to arise from the radiolysis of tryptophan, which is therefore proposed as the initial product of hydroxyl radical attack on the alpha-carbon atom adjacent to the peptide nitrogen. The presence of an aromatic ring in the C-terminal acid (try-tyr, try-phe) results also in hydroxyl radical attack on this ring. (Author)

Descriptors :   (*PEPTIDES, *RADIATION CHEMISTRY), (*TRYPTOPHAN, PEPTIDES), X RAYS, GAMMA RAYS, FREE RADICALS, CANADA

Subject Categories : Biochemistry
      Radiobiology
      Radiation and Nuclear Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE