Accession Number : AD0711289

Title :   THE SYNTHESIS OF NEW ANTIMALARIALS.

Descriptive Note : Research rept.,

Corporate Author : NAVAL ACADEMY ANNAPOLIS MD

Personal Author(s) : Bodnar,John W.

Report Date : 15 MAY 1970

Pagination or Media Count : 71

Abstract : The appearance of drug-resistant strains of malaria in Vietnam has led to an intensified search for new antimalarials, coordinated by the Walter Reed Army Institute of Research. As a part of this program, the following derivatives of carbazole and the necessary intermediates have been synthesized: (C12H8N)C(=R')R where R= CH3, CH2CH3, C6H5; and R'=NOH, NNHC(=NH)NH2, NNHC(=S)NH2. (Author)

Descriptors :   (*ANTIMALARIALS, SYNTHESIS(CHEMISTRY)), GUANIDINES, HYDRAZONES, NITROGEN HETEROCYCLIC COMPOUNDS

Subject Categories : Pharmacology
      Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE