Accession Number : AD0711625

Title :   HYPERBARIC OXYGEN ENHANCEMENT OF COXSACKIE VIRUS B-1 INFECTION IN YOUNG MICE.

Descriptive Note : Technical rept.,

Corporate Author : SETON HALL UNIV SOUTH ORANGE N J DEPT OF BIOLOGY

Personal Author(s) : Orsi,E. V. ; Mancini,R. ; Barriso,J.

Report Date : 09 SEP 1970

Pagination or Media Count : 14

Abstract : This study presents the results obtained with mice subjected to combined coxsackievirus infection and hyperbaric oxygenation. Coxsackie virus was chosen because of its ubiquitous human distribution along with predictable decreasing sensitivity in mice with increasing age. Consequently, this system afforded a potential human hazard model of enhanced viral susceptibility against a background of decreased host sensitivity. In addition, preliminary experiments in our laboratory with cell cultures, poliovirus, and coxsackie virus had indicated greater hyperbaric enhancement with the latter virus. A detailed report of these experiments is in preparation. (Author)

Descriptors :   (*COXSACKIE VIRUS, OXYGEN), (*VIRUS DISEASES, *OXYGEN), (*IMMUNITY, INHIBITION), ENVIRONMENT, MICE, SENSITIVITY, RESISTANCE(BIOLOGY), STRESS(PHYSIOLOGY), INFECTIONS, VIRUSES

Subject Categories : Stress Physiology
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE