Accession Number : AD0711863

Title :   STUDIES ON TICK-BORNE ENCEPHALITIS AND OTHER ARTHROPOD-BORNE VIRUS DISEASES.

Descriptive Note : Final technical rept.,

Corporate Author : VIENNA UNIV (AUSTRIA) HYGIENE INST

Personal Author(s) : Kunz,Ch. ; Aspoeck,H. ; Frisch-Niggemeyer,W. ; Hofmann,H. ; Radda,A.

Report Date : JUL 1970

Pagination or Media Count : 79

Abstract : Foci of TBE virus were found for the first time in Carinthia. Two new foci were found in Upper Austria. Polyphosphoinositides (PPI) were extracted from monkey brain, purified and chemically analyzed. They inhibit competitively the hemagglutination of all viruses of group B so far tested and of Semliki Forest virus of group A. Infectivity of West Nile virus is also inhibited. Poly I:C given mice before intracerebral infection with TBE virus reduced the number of fatalities. Male Ixodes ricinus whose bite is seldom noticed, transmit TBE virus. Cats and stoats can act as hosts of TBE virus. Roe deer is no reservoir animal of TBE virus. Inoculation of ribonuclease into ticks during eclipse phase of TBE virus abolished infectivity. Tahyna virus was active in the Neusiedlersee area in 1968 and 1969. The incidence of Calovo virus was only found in 1969. Cattle are the main vertebrate hosts of Calovo virus. Application of dimethylsulfoxide considerably increases levels of interferon found in sera of mice after infection with Calovo and Sindbis viruses. After passages in baby hamsters, 'Marburg virus' became pathogenic for newborn mice. (Author)

Descriptors :   (*ARBOVIRUSES, DISEASES), (*VIRUS DISEASES, AUSTRIA), DISEASE VECTORS, ECOLOGY, DISTRIBUTION, GEOGRAPHY, CULICIDAE, TICKS, MAMMALS, SERODIAGNOSIS, INFECTIONS, INFECTIOUS DISEASES, RODENTS, ARTHROPODA, SULFOXIDES, AUSTRIA, RIBONUCLEASE, PHOSPHOLIPIDS

Subject Categories : Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE