Accession Number : AD0712180

Title :   NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY OF THE TRIMETHYLSILYL ETHERS OF SOME HYDROXYPHENYLALKYLAMINES,

Corporate Author : NATIONAL RESEARCH COUNCIL OF CANADA HALIFAX (NOVA SCOTIA) ATLANTIC REGIONAL LAB

Personal Author(s) : Forrest,Janet E. ; Heacock,R. A. ; Forrest,T. P.

Report Date : 23 JAN 1970

Pagination or Media Count : 7

Abstract : A number of hydroxyphenylalkylamines have been converted into their trimethylsilyl ethers by the action of hexamethyldisilazane in pyridine. The derivatives are completely soluble in carbon tetrachloride and these solutions are suitable for nuclear magnetic resonance spectroscopy. The nmr spectra of 16 potentially biologically active phenylalkylamines have been obtained in this way. The spectral data are presented and the significance of the results discussed. (Author)

Descriptors :   (*AMINES, *NUCLEAR MAGNETIC RESONANCE), (*EPINEPHRINE, NUCLEAR MAGNETIC RESONANCE), SILANES, CANADA

Subject Categories : Medicine and Medical Research
      Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE