Accession Number : AD0712957

Title :   CALCIUM BINDING PROTEIN: ENDOGENOUS INDUCTION.

Descriptive Note : Interim rept.,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : Morrissey,Robert L. ; Hysell,David K. ; Janik,Willie L.

Report Date : 13 MAR 1970

Pagination or Media Count : 12

Abstract : Endogenous induction of CaBP was demonstrated in rachitic chicks by surgically isolating a segment of duodenum from the functioning portion, leaving its blood supply intact, followed by oral administration of vitamin D3. CaBP was induced in the nonfuctioning segment, indicating that the lumenal environment is not critical to the induction of the protein. Thus, adaptation to various dietary calcium concentrations is likely to occur via endogenous regulating factors, rather than due to a direct effect of pH or calcium concentration in the duodenal lumen. (Author)

Descriptors :   (*CALCIUM, CHEMICAL BONDS), (*PROTEINS, CALCIUM), (*NUTRITION, CALCIUM), ABSORPTION(BIOLOGICAL), VITAMIN D, ADAPTATION(PHYSIOLOGY), INTESTINES, DIET, CONTROL

Subject Categories : Biochemistry
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE