Accession Number : AD0712985

Title :   STRESS AND THE ADRENOCORTICAL RESPONSE: ENRICHED PAST EXPERIENCE REDUCES THE STRESS RESPONSE.

Descriptive Note : Technical memo.,

Corporate Author : HUMAN ENGINEERING LABS ABERDEEN PROVING GROUND MD

Personal Author(s) : Hudgens,Gerald A.

Report Date : AUG 1970

Pagination or Media Count : 14

Abstract : First-litter male Wistar rats were either handled or not handled on Days 1-15 following birth. In adulthood they were exposed for three minutes to a large open field for one, two, three or four days. Fifteen minutes after the last exposure they were sacrificed and free plasma corticosterone was assayed. Handled subjects showed a significantly lower adrenocortical response to the open field than non-handled subjects. This finding supports the previously reported open-field findings from these same subjects (Hudgens, 1970) which showed that early handled subjects react less emotionally when exposed to a novel environment. The mothers were re-bred twice to rear second and third litters which were not handled in infancy. These litters received four days of open-field testing before being sacrificed. No differences were obtained on the corticosterone measure as a function of the mothers' first litters being handled or non-handled. Some methodological difficulties are discussed. (Author)

Descriptors :   (*STRESS(PSYCHOLOGY), ADRENAL CORTEX), (*ADRENAL CORTEX, *PSYCHOPHYSIOLOGY), RESPONSE(BIOLOGY), PHYSIOLOGY, BEHAVIOR, EMOTIONS, CORTICOSTEROID AGENTS, RATS

Subject Categories : Psychology
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE