Accession Number : AD0713169

Title :   CATABOLIC PHASE OF HEMIN CHROMOPROTEIN METABOLISM,

Corporate Author : PENNSYLVANIA UNIV PHILADELPHIA DEPT OF BIOCHEMISTRY

Personal Author(s) : Drabkin,David L.

Report Date : 1968

Pagination or Media Count : 9

Abstract : A brief summary is given of work which involved the following specific investigations: Level of output of bile pigment; Potential of hemoglobin breakdown to bile pigment; Role of haptoglobin; Breakdown of injected myoglobin, cytochrome c, denatured hemoglobin, and hematin solutions of pH 8.5 to bile pigment; Role of the liver in hemin chromoprotein breakdown; Reticuloendothelial system; Liver perfusion experiments; The hemophagous organ; A new cell-free enzyme system, prepared from the hemophagous organ and capable of degrading hemin and hemoglobin to biliverdin; and Production of carbon monoxide in the process of bile pigment production from hemin and hemoglobin.

Descriptors :   (*CHROMOPROTEINS, *METABOLISM), HEMOGLOBIN, BILE PIGMENTS, ENZYMES, CYTOCHROME OXIDASE, LIVER, RETICULOENDOTHELIAL SYSTEM, CARBON MONOXIDE, PLACENTA

Subject Categories : Biochemistry
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE