Accession Number : AD0713169
Title : CATABOLIC PHASE OF HEMIN CHROMOPROTEIN METABOLISM,
Corporate Author : PENNSYLVANIA UNIV PHILADELPHIA DEPT OF BIOCHEMISTRY
Personal Author(s) : Drabkin,David L.
Report Date : 1968
Pagination or Media Count : 9
Abstract : A brief summary is given of work which involved the following specific investigations: Level of output of bile pigment; Potential of hemoglobin breakdown to bile pigment; Role of haptoglobin; Breakdown of injected myoglobin, cytochrome c, denatured hemoglobin, and hematin solutions of pH 8.5 to bile pigment; Role of the liver in hemin chromoprotein breakdown; Reticuloendothelial system; Liver perfusion experiments; The hemophagous organ; A new cell-free enzyme system, prepared from the hemophagous organ and capable of degrading hemin and hemoglobin to biliverdin; and Production of carbon monoxide in the process of bile pigment production from hemin and hemoglobin.
Descriptors : (*CHROMOPROTEINS, *METABOLISM), HEMOGLOBIN, BILE PIGMENTS, ENZYMES, CYTOCHROME OXIDASE, LIVER, RETICULOENDOTHELIAL SYSTEM, CARBON MONOXIDE, PLACENTA
Subject Categories : Biochemistry
Anatomy and Physiology
Distribution Statement : APPROVED FOR PUBLIC RELEASE