Accession Number : AD0713867

Title :   Microbial Drug Resistance (Epidemiology, Genetics).

Descriptive Note : Rept. no. 4 (Annual), Mar 69-Mar 70,

Corporate Author : INSTITUTE OF MICROBIAL CHEMISTRY TOKYO (JAPAN)

Personal Author(s) : Mitsuhashi,Susumu

Report Date : OCT 1970

Pagination or Media Count : 17

Abstract : The strains of Staphylococcus aureus, Escherichia coli, Pseudomonous, Proteus and Klebsiella-Aerobactea, are isolated most frequently from clinical specimens, and should be noted that most of them are multiple-resistant to antibacterial agents that are generally used in hospitals. A collection has been made of many bacterial strains from patients at hospitals which are geographically dispersed in Japan. Their biological and biochemical properties have been studied according to the usual bacterial technics. Resistance to about 30 antibacterial agents was assayed, and biochemical and genetic studies of bacterial drug-resistance were conducted. This report has aimed specially on the problem of drug-resistance of staphylococci. Contents: Transduction analysis of the genetic determinants for antibiotic resistance in S. aureus; Lability of Streptomycin(SM) resistance in S. aureus; Macrolide resistance in S. aureus; Mechanisms of Tetracycline(TC) resistance in S. aureus. (Author)

Descriptors :   (*ANTIBIOTICS, BACTERIA), (*BACTERIA, TOLERANCES(PHYSIOLOGY)), CHEMOTHERAPEUTIC AGENTS, GENETICS, MUTATIONS, STAPHYLOCOCCUS AUREUS, STREPTOMYCINS, TETRACYCLINES, BACTERIOPHAGES, JAPAN

Subject Categories : Microbiology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE