Accession Number : AD0715396

Title :   Neurotropic Effects in Relation to Chemical Structure.

Descriptive Note : Quarterly rept. no. 1, 1 Aug-31 Oct 66,

Corporate Author : SAINT LOUIS UNIV MO

Personal Author(s) : Donahoe,Hugh B. ; Hufker,William J.

Report Date : 31 OCT 1966

Pagination or Media Count : 28

Abstract : In the period covered by this report the preparation of a series of 11-(gamma-aminopropyl)-9,10-ethano-9,10-dihydroanthracene derivatives are described. The synthesis of a variety of (alkoxy)-9,10-ethano-9,10-dihydroanthracenes derivatives and secondary 11-(beta-aminoethyl)-9,10-ethano-9,10-dihydroanthracenes is also reported. Attempts to resolve selected derivatives of 11-(aminomethyl)-9,10-ethano-9,10-dihydroanthracene into their dextro and levo forms were made. (Author)

Descriptors :   (*ANTISPASMODIC AGENTS, *MOLECULAR STRUCTURE), (*AMINES, SYNTHESIS(CHEMISTRY)), (*ANTHRACENES, SYNTHESIS(CHEMISTRY)), (*ANALGESICS + ANTIPYRETICS, MOLECULAR STRUCTURE), MUSCLE RELAXANTS, CARBOXYLIC ACIDS, AMIDES, REDUCTION(CHEMISTRY)

Subject Categories : Pharmacology
      Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE