Accession Number : AD0715702

Title :   Biological Alterations Occurring During Red Cell Preservation.

Descriptive Note : Interim rept.,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : Shields,Charles E. ; Kaplan,Harold S. ; Dawson,Roy B. , Jr

Report Date : 23 JUL 1970

Pagination or Media Count : 17

Abstract : Chemical analysis of stored blood was studied under a variety of environmental stresses. These stresses accentuate changes resulting from storage. The changes were observed in units in storage for at least 2 weeks, subjected to a temperature stress of 22 C with and without mechanical agitation. Units of packed red cells demonstrated similar effects of a slightly greater magnitude. Units left undisturbed and sampled from the top and bottom layers of the sedimented cells showed a different electrolyte distribution. Moreover, the layers exhibited a different oxygen carrying capacity that may be related to alternations in biochemical or electrolyte balance. (Author)

Descriptors :   (*BLOOD, PRESERVATION), EFFECTIVENESS, ERYTHROCYTES, METABOLISM, BIOCHEMISTRY, THERMAL STRESSES, STRAIN(MECHANICS), HEMOLYSIS, OXYGEN, STORAGE, STRESSES, ENVIRONMENT, CHEMICAL ANALYSIS

Subject Categories : Biochemistry
      Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE