Accession Number : AD0715732
Title : An Investigation of Bonding Mechanisms at the Interface of a Prosthetic Material.
Descriptive Note : Annual rept. no. 1, 31 Aug 69-31 Jul 70,
Corporate Author : FLORIDA UNIV GAINESVILLE DEPT OF METALLURGICAL AND MATERIALS ENGINEERING
Personal Author(s) : Hench,L. L. ; Greenlee,T. K. ; Allen,W. C.
Report Date : AUG 1970
Pagination or Media Count : 63
Abstract : The two primary objectives of this program are: (1) to achieve a direct chemical bond between orthopaedic devices and bone using glass and glass-ceramic materials or coatings, and (2) to develop a scientific understanding of the interfacial reactions occurring between materials and bone. The report summarizes evidence developed in this laboratory of direct chemical bonding between glass-ceramic implants and rat femurs. A comparison of morphologic techniques developed for the evaluation of the bone-ceramic interface is presented. In-vitro studies of hydroxyapatite crystallization on glass-ceramics have shown bonding of the bone mineral to the implant material. The kinetics of interfacial solubility and pH changes of the implants have also been measured. A preliminary histo-physio-chemical model for the interfacial reactions leading to direct chemical bonding is advanced based on in-vitro and in-vivo studies. (Author)
Descriptors : (*BONES, *BONDING), (*PROSTHETICS, BONDING), CERAMIC MATERIALS, GLASS, CHEMICAL BONDS, INTERFACES, ADHESIVES, MICROSTRUCTURE, CRYSTALLIZATION, ELECTRON MICROSCOPY
Subject Categories : Medical Facilities, Equipment and Supplies
Distribution Statement : APPROVED FOR PUBLIC RELEASE