Accession Number : AD0715749

Title :   Steroid Hormones in the Preservation of Human Blood.

Descriptive Note : Interim rept.,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : DeVenuto,Frank ; Wilson,Sarah M.

Report Date : 09 NOV 1970

Pagination or Media Count : 14

Abstract : Progesterone is effective in protecting erythrocytes during storage by minimizing spontaneous lysis, changes in osmotic resistance and loss of ATP. The greatest effect is obtained by addition of progesterone plus adenine to erythrocytes suspended in phosphate buffer. Testosterone and androsterone are without effect. The use of the 'osmotic fragility index' to represent the osmotic resistance of erythrocytes is proposed. (Author)

Descriptors :   (*BLOOD, PRESERVATION), (*HORMONES, BLOOD), STEROIDS, STORAGE, ERYTHROCYTES, EFFECTIVENESS, OSMOTIC PRESSURE, ADENOSINE PHOSPHATES, ADENINE, PROGESTERONE, TESTOSTERONE, BIOCHEMISTRY

Subject Categories : Biochemistry
      Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE