Accession Number : AD0717851

Title :   Responses in the Cardiovascular System of Rats Intermittently Exposed to an Altitude of 18,000 Feet.

Descriptive Note : Interim rept. Oct 69-Jun 70,

Corporate Author : SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s) : Foster,Lloyd L.

Report Date : DEC 1970

Pagination or Media Count : 19

Abstract : The study involved a comparison of ground-level rats to rats that were exposed to an altitude of 18,000 feet, six hours a day, for 5, 10, 15, and 20 days, respectively, in order to determine any differences in the responses of the cardiovascular system. Upon comparison of the two groups, the 10, 15, and 20-day altitude rats showed a significant increase in diastolic pressure and systolic pressure. The 10-day altitude group also had an increase in heart rate. Exposure of rats to an altitude of 18,000 feet, six hours a day for 5 days, showed no changes in the cardiovascular measurements when compared to ground-level rats. Intravenous injection of epinephrine increased blood pressure in all groups of rats; this was more pronounced in the 10, 15, and 20-day ground-level group. The 5-day ground level and altitude groups showed no difference in blood pressure rise after the injection of epinephrine. (Author)

Descriptors :   (*CARDIOVASCULAR SYSTEM, HIGH ALTITUDE), STRESS(PHYSIOLOGY), PHYSIOLOGY, HEART, BLOOD PRESSURE, HYPOXIA, EPINEPHRINE, RATS

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE