Accession Number : AD0719997

Title :   Sterol Structure and Ordering Effects in Spin-Labelled Phospholipid Multibilayer Structures,

Corporate Author : NATIONAL RESEARCH COUNCIL OF CANADA OTTAWA (ONTARIO) BIOCHEMISTRY LAB

Personal Author(s) : Butler,K. W. ; Smith,I. C. P. ; Schneider,H.

Report Date : 07 SEP 1970

Pagination or Media Count : 5

Abstract : Cholesterol is a common component of vertebrate cellular membranes. Sterols with a similar structure (3beta-OH group, hydrocarbon chain at position 17) are also found in vascular plants, algae, fungi, and microorganisms. The biological function of these compounds is not completely understood. The authors investigated the effects of steroid structure on the degree of order in multibilayer structures of polar membrane lipids using a spin label technique. The results indicate that cholesterol and structurally related sterols increase the degree of order of the spin label, and hence that of the lipids in the lamellar structure. (Author)

Descriptors :   (*PHOSPHOLIPIDS, *MEMBRANES(BIOLOGY)), (*ELECTRON PARAMAGNETIC RESONANCE, PHOSPHOLIPIDS), CHOLESTEROL, MOLECULAR STRUCTURE, STEROIDS, CANADA

Subject Categories : Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE