Accession Number : AD0720411

Title :   The Role of Water-Salt Metabolism in the Etiology and Pathogenesis of Decompression Sickness (K Voprosy o Roli Vodno-Solevogo Obmena v Etiologii i Patogeneze Decompressionnoi Bolezni),

Corporate Author : SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s) : Shostak,V. I. ; Averyanov,V. A.

Report Date : 1971

Pagination or Media Count : 7

Abstract : Despite numerous investigations into the etiology and pathogenesis of decompression sickness (caisson disease), much remains to be explained at present. In particular, the complex chain of pathological reactions, arising in the organism upon the formation of gas bubbles in the tissues and following the development of the disease, is still not very clear. Experimental results of investigations produced the following conclusions: The water-salt metabolism plays a substantial role in the etiology and pathogenesis of decompression sickness (caisson disease). Intraperitoneal administration of distilled water to mice 90 minutes before the animals are placed in a compression chamber causes a sharp reduction in the frequency of sickness in comparison with the control animals. The reduction in the frequency of disease after the administration of distilled water to the animals is evidently connected with a higher capacity of the fluids and tissues of the body to maintain nitrogen in a supersaturated state. (Author)

Descriptors :   (*DECOMPRESSION SICKNESS, METABOLISM), ETIOLOGY, WATER, ELECTROLYTES(PHYSIOLOGY), STRESS(PHYSIOLOGY), PHYSIOLOGY, USSR

Subject Categories : Medicine and Medical Research
      Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE