Accession Number : AD0721064

Title :   Behavioural Thermoregulation and Cold Adaptation in Two Strains of White Mice,

Corporate Author : DEFENCE RESEARCH ESTABLISHMENT TORONTO DOWNSVIEW (ONTARIO)

Personal Author(s) : Ogilvie,D. M.

Report Date : 22 JUL 1970

Pagination or Media Count : 7

Abstract : Survival and degree of cold adaptation were determined for Swiss Webster and Connaught strain white mice exposed to 2C and caged as follows: (I) a single animal in an empty plastic cage; (II) a single animal in a plastic cage containing bedding material; (III) 2 animals in an empty wire-mesh cage, and (IV) 3 animals in a plastic cage containing bedding material. After 10 days of exposure under these conditions, survival was 54, 62, 87 and 94% in Swiss Webster, and 87, 100, 92 and 92% in Connaught mice. When the degree of cold adaptation was estimated on the basis of the average decrease in core temperature during a 45-minute exposure to -10C, values of 4.4 (I), 5.1 (II), 4.2 (III), 6.8 (IV) and 11.0C (control) were determined for Swiss Webster mice, and 1.7 (I, II and III), 3.2 (IV) and 9.0C (control) for Connaught mice. The study revealed that there are significant intrastrain differences in the ability of small mammals to both tolerate and adapt to a cold stress. (Author)

Descriptors :   (*LOW TEMPERATURE, *MICE), (*BEHAVIOR, LOW TEMPERATURE), (*BODY TEMPERATURE, LOW TEMPERATURE), (*STRESS(PHYSIOLOGY), LOW TEMPERATURE), ADAPTATION(PHYSIOLOGY), TOLERANCES(PHYSIOLOGY), ANIMALS, MAMMALS, EXPERIMENTAL DATA

Subject Categories : Anatomy and Physiology
      Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE