Accession Number : AD0724142

Title :   Bioparameters of Human Red Blood Cells of Two Different Age Groups.

Descriptive Note : Interim rept.,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : DeVenuto,Frank ; Santella,Dennis

Report Date : 16 MAR 1971

Pagination or Media Count : 15

Abstract : A correlation exists between the increase of specific gravity and the decrease in osmotic resistance as storage time of red cells is prolonged to a period of 42 days. Young and old cells show differences in osmotic fragility, spontaneous hemolysis, activity of G-6-PD and ATP levels. Membrane preparations from the two groups of cells, upon fractionation by disc electrophoresis, demonstrate electrophoretic patterns which are qualitatively and quantitatively different. (Author)

Descriptors :   (*ERYTHROCYTES, *BIOCHEMISTRY), (*BIOPHYSICS, ERYTHROCYTES), (*BLOOD, STORAGE), AGING(PHYSIOLOGY), GRAVITY, HEMOLYSIS, OSMOTIC PRESSURE, PHYSIOLOGY, METABOLISM, ENZYMES, HEMATOLOGY, MEMBRANES(BIOLOGY)

Subject Categories : Biochemistry
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE