Accession Number : AD0729973

Title :   Mechanisms of Hemolysis.

Descriptive Note : Annual summary rept.,

Corporate Author : CALIFORNIA UNIV SAN DIEGO LA JOLLA SCHOOL OF MEDICINE

Personal Author(s) : Bernstein,Eugene F.

Report Date : AUG 1971

Pagination or Media Count : 46

Abstract : Wall or surface interaction trauma did not result in striking or significant changes or erythrocyte ATP concentration, or 2,3-diphosphoglycerate concentration. The phosphate concentration of the suspending medium has a critical effect upon the maintenance of both ATP and 2,3-diphosphoglycerate concentration in the erythrocyte, and, secondarily, upon shifts in the oxyhemoglobin dissociation curve. A suitable device for selective shear stress damage has been constructed, and is presently in operation. (Author)

Descriptors :   (*HEMOLYSIS, CELL WALL), SHEAR STRESSES, ERYTHROCYTES, ADENOSINE PHOSPHATES, HEMOGLOBIN

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE