Accession Number : AD0732388

Title :   Physicochemical Changes in Erythrocyte Membranes during Cold Storage in the Presence of Progesterone.

Descriptive Note : Interim rept.,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : Moore,Gerald L. ; Antonoff,Ross S. ; Rau,Donald C.

Report Date : 30 JUN 1971

Pagination or Media Count : 10

Abstract : Red cells were stored for 42 days, with and without added progesterone, and at 14 day intervals stroma was prepared from these red cells for analysis by various physicochemical methods. Progesterone appears to bind to the erythrocyte membrane proteins, causing a change in their structure which 'locks' them into a stabilized state that is more or less constant for at least 28 days, then starts to wear off or dissociate. (Author)

Descriptors :   (*BLOOD, STORAGE), (*PROGESTERONE, BLOOD), (*ERYTHROCYTES, MEMBRANES(BIOLOGY)), PRESERVATION, HORMONES, PROTEINS, STABILITY, HEMOLYSIS, BIOCHEMISTRY, BIOPHYSICS

Subject Categories : Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE