Accession Number : AD0736228

Title :   Enzymes of Plaque Polysaccharides and Dental Caries Incidence.

Descriptive Note : Annual rept. no. 1, Jan-Dec 71,

Corporate Author : TUFTS UNIV BOSTON MASS SCHOOL OF DENTAL MEDICINE

Personal Author(s) : Manly,Richard S.

Report Date : 26 JAN 1972

Pagination or Media Count : 15

Abstract : Plaque samples from 50 subjects have been obtained in cooperation with the Great Lakes Naval Training Center. These samples were analyzed to determine the activity of the following enzymes--levansucrase, dextrane-sucrase, levanase, and dextranase. It was found necessary to incubate and inactivate the samples before shipment to us. Initial results indicated that only levansucrase, dextransucrase and levanase are present in caries-active subjects and only dextranase dextranase is present in caries-immune subjects. Analysis of samples in June, 1971 indicated a greater activity of the synthetic enzymes in caries-active subjects. The results from analyses of the subsequent samples (38 subjects) showed little or no enzyme activity. It was determined that the most likely reason for the sudden difference in plaque enzyme activity was a change in sample handling procedure prior to the incubation and inactivation steps. (Author)

Descriptors :   (*ENZYMES, DENTISTRY), (*POLYSACCHARIDES, DENTISTRY), IMMUNITY, TEETH, PATHOLOGY, METABOLISM, DEXTRAN

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE