Accession Number : AD0737562

Title :   Bronsted Coefficient for the Nucleophilic Attack of Hydroxamate Ions on Di-isopropyl Phosphorochloridate,

Corporate Author : DEFENCE RESEARCH ESTABLISHMENT OTTAWA (ONTARIO)

Personal Author(s) : Weinberger,M. A. ; Greenhalgh,R. ; Lutley,P. M. ; Gibson,N. C. C.

Report Date : 07 DEC 1970

Pagination or Media Count : 4

Abstract : The Bronsted coefficient for the reaction of di-isopropyl phosphorochloridate with a series of four hydroxamate ions has been determined. The implication of its value, 0.21, inasmuch as it is related to charge transfer in the transition state for the phosphylation of a nucleophile, is discussed in relation to the product selectivity with an ambident nucleophile, 2-aminoethanol. (Author)

Descriptors :   (*HYDROXAMIC ACIDS, CHEMICAL REACTIONS), (*ORGANIC PHOSPHORUS COMPOUNDS, CHEMICAL REACTIONS), PHOSPHORYLATION, ACID BASE EQUILIBRIUM, AMINES, REACTION KINETICS, AMINES, CANADA

Subject Categories : Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE