Accession Number : AD0737671

Title :   Studies of Fluorometric Assay Procedures for Lysergic Acid Diethylamide,

Corporate Author : ARMY AEROMEDICAL RESEARCH LAB FORT RUCKER ALA

Personal Author(s) : Kasvinsky,Peter J.

Report Date : FEB 1972

Pagination or Media Count : 16

Abstract : Studies of the available fluorometric assay procedures for LSD-25 are described for possible clinical application. Variability of plasma 'blank' background fluorescence values were found to prohibit the use of standard fluorometric procedures without modification. A little known fluorometric procedure is described which minimuzes this problem and maintains the sensitivity of the assay at the nanogram level. Modifications of this method are suggested which could increase the sensitivity of this method to the subnanogram level. (Author)

Descriptors :   (*LYSERGIC ACIDS, *BLOOD CHEMISTRY), (*HALLUCINOGENS, BLOOD CHEMISTRY), FLUORESCENCE, IN VITRO ANALYSIS, EXCITATION, BLOOD PLASMA, MICROANALYSIS

Subject Categories : Biochemistry
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE