Accession Number : AD0738285

Title :   Features Peculiar to Nicotinic Acid Metabolism in Acute Respiratory Diseases,

Corporate Author : FORT DETRICK FREDERICK MD

Personal Author(s) : Starshov,P. D. ; Ostapenko,A. S.

Report Date : 1972

Pagination or Media Count : 6

Abstract : During sporadic acute respiratory sicknesses, tonsillitis, and pneumonia, stereotypic deviations in the metabolism of nicotinic acid, including decreased level of pyridine nucleotides in whole blood and erythrocytes and in raised spontaneous removal in the urine of N1-methylnicotinamid and its 6-pyridon were observed. Expressivity and duration of metabolic shifts of nicotinic acid is found in direct relation to the intensity and duration of inflamatory changes of the breathing apparatus. To compensate for the losses of nicotinic acid in the acute phase of the disease, addition of the vitamin in the food in a daily dose of 40>80mg, granulated, was ordered.

Descriptors :   (*RESPIRATORY DISEASES, NICOTINIC ACID), (*NICOTINIC ACID, METABOLISM), INFECTIOUS DISEASES, RESPIRATION, TISSUES(BIOLOGY), PYRIDINES, NUCLEOTIDES, RESPIRATORY SYSTEM, USSR

Subject Categories : Biochemistry
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE