Accession Number : AD0745393

Title :   Schistosomiasis Drug Screening.

Descriptive Note : Rept. no. 10 (Annual), Jun 71-May 72,

Corporate Author : UNIVERSIDADE FEDERAL DE MINAS GERAIS BELO HORIZONTE (BRAZIL) INSTITUTO DE CIENCIAS BIOLOGICAS

Personal Author(s) : Pellegrino,J.

Report Date : MAY 1972

Pagination or Media Count : 26

Abstract : From a total of 5,000 WR compounds which have been screened so far, 75 have been found to produce oogram changes in laboratory animals infected with Schistosoma mansoni. The antischistosomal activity of quinine and isomers, thiosinamine, diphenylsulfones, triphenyl bismuth, nitrofurazone, quinoline methanols, phenolphtalein, nitrothiazoles, aminothiols, etc. have been discussed in previous reports. The present report summarizes the antischistosomal activity of 15 additional compounds.

Descriptors :   (*ANTHELMINTICS, *SCHISTOSOMA), DRUGS, LABORATORY ANIMALS, BIOASSAY, PHARMACOLOGY, PARASITIC DISEASES, BRAZIL

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE