Accession Number : AD0745401

Title :   Effects of Intravenous Hyperalimentation on the Metabolic Response to Trauma.

Descriptive Note : Annual rept. no. 1,

Corporate Author : PENNSYLVANIA UNIV PHILADELPHIA DEPT OF SURGERY

Personal Author(s) : Dudrick,Stanley J.

Report Date : 31 JUL 1972

Pagination or Media Count : 32

Abstract : The technique of intravenous hyperalimentation has been used to study the effects and results of total parenteral feeding on the metabolic response to surgical or accidental trauma in laboratory animals and patients. Measurements of nitrogen balance, urine and serum electrolytes, and serum and urine amino acid patterns have been evaluated under a myriad of clinical conditions with carefully controlled input of nutrients. A newly developed total intravenous technique for small laboratory animals has been used to demonstrate the beneficial effects of post-operative nutrition of the healing of colon anastomoses in protein-depleted rats. The safety of the central venous catheters used for intravenous hyperalimentation has been reaffirmed by a prospective study of infectious complications, showing less than 4 percent incidence of catheter sepsis. (Author)

Descriptors :   (*PARENTERAL INFUSIONS, METABOLISM), (*SHOCK(PATHOLOGY), PARENTERAL INFUSIONS), NUTRITION, CANNULATION, SURGERY, THERAPY, PATHOLOGY, PHYSIOLOGY

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE