Accession Number : AD0747330
Title : Behavior, Ecology and Toxicity of Venomous Marine Fishes.
Descriptive Note : Rept. no. 21 (Quarterly technical) 1 Apr - 30 Jun 72,
Corporate Author : PROFESSIONAL STAFF ASSOCIATION OF LAC/USC MEDICAL CENTER LOS ANGELES CALIF
Personal Author(s) : Russell,Findlay E.
Report Date : 30 JUN 1972
Pagination or Media Count : 2
Abstract : The hemodynamic properties of the venom of the California scorpionfish were studied in rabbits, cats, dogs, guinea pigs, rats and mice. The rabbit was found to be the most sensitive mammal to the lethal activity, whereas the shore crab was the most resistant animal studied. In the mammal, intravenous injection of venom caused acute prostration, systemic arterial hypotension, respiratory distress, pulmonary artery hypertension, pulmonary edema, electrocardiographic alterations, convulsive-like movements, weakness and death. Although the venom affected respiration, the death of ventilated and non-ventilated animals was associated with major cardiac arrhythmias and/or arterial hypotension. Cardiac standstill could be produced with doses greater than the LD50.
Descriptors : (*VENOMS, *FISHES), MARINE BIOLOGY, BIOASSAY, LABORATORY ANIMALS, TOXICITY, PATHOLOGY, BLOOD CIRCULATION, PHYSIOLOGY
Subject Categories : Toxicology
Distribution Statement : APPROVED FOR PUBLIC RELEASE