Accession Number : AD0748795

Title :   Neuropharmacology and Experimental Psychiatry. The Evolution of a Project--A Progress Report,

Corporate Author : MISSOURI UNIV ST LOUIS INST OF PSYCHIATRY

Personal Author(s) : Marrazzi,Amedeo S.

Report Date : 1970

Pagination or Media Count : 45

Abstract : By means of a correlative, interdisciplinary approach analyzing performance at all levels, it has been possible to gain a more insightful understanding of the uniquely comprehensive functions of the nervous system, which displays man's environments translated into information signals, develop the required solutions and convert them into the necessary command signals. These studies have highlighted the capabilities of the cerebral computer for maintaining homeostasis and the devastating consequences--mental and bodily--when homeostasis or adaptation at the key level of central representation fails and constitutes mental illness. A critical communication link between brain cells is chemical, and therefore would be expected to be and is modifiable by other chemicals and drugs accounts for the amenability to analysis and to correction by drugs. It has been found that this special interneuronal chemical transmitter environment appears to be the substrate for the action of the most potent cerebral drugs. (Author)

Descriptors :   (*PHARMACOLOGY, *PSYCHIATRY), MENTAL DISORDERS, DRUGS, NERVOUS SYSTEM, PSYCHOTROPIC AGENTS, BRAIN, NEUROLOGY, BEHAVIOR, CNS DEPRESSANTS, CNS STIMULANTS

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE