Accession Number : AD0749763

Title :   The Distribution of Dose in Time during Radiation Therapy of Malignant Tumors,

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Balmukhanov,S. B. ; Zholkiver,K. I.

Report Date : 05 MAY 1972

Pagination or Media Count : 27

Abstract : In 1920 Seitz and Wintz proposed the method of the single massive irradiation of malignant tumors, however they soon rejected it because X-ray therapy could not ensure the necessary degree of sterilization of the tumor. Furthermore serious damages to normal tissues appeared simultaneously. The magnitude of carcinocidal dose is determined to a considerable degree by the regularities in the relationship of radiosensitivity of various tissues which were revealed already in 1905 by Bergonie and Tribondeau. Ancel and Vintemberger established that the manifestation of radiation injury depends on the rate of multiplication of cells which is characteristic for one or another tissue. These investigations served as the premise for various systems for the distribution of dose in time. (Author)

Descriptors :   (*RADIOTHERAPY, *RADIATION DOSAGE), CANCER, NEOPLASMS, X RAYS, RADIATION INJURIES, TISSUES(BIOLOGY), DOSE RATE, DOSIMETERS, USSR

Subject Categories : Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE