Accession Number : AD0751433

Title :   A Study of Liver Microsomal Cytochromes Following Chronic Exposure to Dichloromethane,

Corporate Author : AEROSPACE MEDICAL RESEARCH LAB WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Bullock,F. J. ; Callahan,M. ; Harris,E. S.

Report Date : DEC 1971

Pagination or Media Count : 10

Abstract : It was noted that CCl3CH3 has been reported to result in an increase of cytochrome P-450 as well as NADPH-cytochrome c reductase in rat liver. The chlorocarbon was administered by inhalation at 2500-3000 ppm for 24 hours.

Descriptors :   (*HALOGENATED HYDROCARBONS, *TOXICITY), (*ENZYMES, HALOGENATED HYDROCARBONS), LIVER, RIBOSOMES, OXIDATION, CYTOLOGY, RETICULOENDOTHELIAL SYSTEM, MICE, BIOASSAY, SOLVENTS, EXPOSURE(PHYSIOLOGY), RESPIRATION

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE