Accession Number : AD0756474

Title :   Changes in the Electroretinogram c-Wave Following Laser Insult.

Descriptive Note : Technical rept.,

Corporate Author : TEXAS UNIV AUSTIN ELECTRONICS RESEARCH CENTER

Personal Author(s) : Priebe,Leslie A. ; Sewell,V. L. ; Vogt,F. B. ; Welch,A. J.

Report Date : 01 JUN 1972

Pagination or Media Count : 99

Abstract : The study was conducted to compare changes in the electroretinogram c-wave following ruby laser insult with the threshold for ophthalmoscopically visible lesions. Dark adapted, pigmented rabbits were used as experimental subjects. A corneal ring electrode was used to monitor the electroretinogram. The experimental procedure included recording the pre-burn responses which were evoked by a 27.5 micro J argon stimulus, exposing the retina to ruby laser radiation, and recording the post burn responses at 30-minute intervals for one hour post insult. The data shows an increase in c-wave amplitude for ruby energies from approximately 75 percent to 300 percent of the ophthalmoscopic threshold. The amplitude decreased above 300 percent of threshold. The increases in c-wave amplitude are thought to be caused by increased transretinal potassium flux. The decreases in c-wave amplitude are caused by decreased potassium flux following pigment epithelial cell death. (Author)

Descriptors :   (*ELECTRORETINOGRAPHY, *LASERS), (*OPHTHALMOLOGY, LASERS), EYE, RETINA, RADIATION INJURIES, RADIATION DOSAGE, THRESHOLDS(PHYSIOLOGY), ELECTROPHYSIOLOGY, RABBITS, EXPERIMENTAL DATA, VISUAL PERCEPTION

Subject Categories : Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE