Accession Number : AD0757038

Title :   The Relative Effectiveness of Fission Neutrons for Gastrointestinal Damage in Mice: Lethality and Jejunal Crypt Response.

Descriptive Note : Scientific rept.,

Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD

Personal Author(s) : Zeman,G. H. ; Jones,S. R. ; George,R. E. ; Levin,S. G.

Report Date : SEP 1972

Pagination or Media Count : 20

Abstract : Mice were unilaterally irradiated in either a high neutron or a high gamma ray field. Median doses for gastrointestinal lethality (LD50/6) were 350 rads and 882 rads for the neutron and gamma ray fields, respectively, following single pulsed exposures. Thus, the relative effectiveness of the neutron field at the LD50/6 dose level was 2.5. The percentage of jejunal crypts destroyed at various neutron and gamma ray doses was also determined. The relative effectiveness of the neutron field associated with jejunal crypt destruction ranged from 3.1 at 10 percent crypt destruction to 2.1 at 90 percent. A direct relation between destruction of jejunal crypts and animal lethality was demonstrated. (Author)

Descriptors :   (*FISSION NEUTRONS, *GASTROINTESTINAL SYSTEM), (*RADIATION EFFECTS, FISSION NEUTRONS), RADIATION DOSAGE, RADIATION INJURIES, GAMMA RAYS, MICE, EXPERIMENTAL DATA

Subject Categories : Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE