Accession Number : AD0757155

Title :   Gas-Liquid Chromatographic Assay of 1,2,3-Trimercaptopropane in Dimercaprol.

Descriptive Note : Technical rept. Apr 68-Mar 72,

Corporate Author : EDGEWOOD ARSENAL MD

Personal Author(s) : Cooper,Aubrey E. ; Kondritzer,Albert A.

Report Date : MAR 1973

Pagination or Media Count : 14

Abstract : The report provides a description of studies conducted, using the technique of gas-liquid chromatography, to determine if 1,2,3-Trimercaptopropane (TSH) is present to an extent greater than 1.5 percent in lots of dimercaprol (BAL), which is used in the formulation of FSN 6505-108-8500 Dimercaprol Injection, USP, 10 percent 5 cc. Satisfactory results were obtained using an 18-foot glass column, SE-30 liquid support, and isothermal operation. (Author)

Descriptors :   (*THIOLS, *GAS CHROMATOGRAPHY), IMPURITIES, PROPANOLS

Subject Categories : Pharmacology
      Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE