Accession Number : AD0757155
Title : Gas-Liquid Chromatographic Assay of 1,2,3-Trimercaptopropane in Dimercaprol.
Descriptive Note : Technical rept. Apr 68-Mar 72,
Corporate Author : EDGEWOOD ARSENAL MD
Personal Author(s) : Cooper,Aubrey E. ; Kondritzer,Albert A.
Report Date : MAR 1973
Pagination or Media Count : 14
Abstract : The report provides a description of studies conducted, using the technique of gas-liquid chromatography, to determine if 1,2,3-Trimercaptopropane (TSH) is present to an extent greater than 1.5 percent in lots of dimercaprol (BAL), which is used in the formulation of FSN 6505-108-8500 Dimercaprol Injection, USP, 10 percent 5 cc. Satisfactory results were obtained using an 18-foot glass column, SE-30 liquid support, and isothermal operation. (Author)
Descriptors : (*THIOLS, *GAS CHROMATOGRAPHY), IMPURITIES, PROPANOLS
Subject Categories : Pharmacology
Distribution Statement : APPROVED FOR PUBLIC RELEASE