Accession Number : AD0759405

Title :   The Effects of Oxygen at High Pressure on Catecholamine Metabolism.

Descriptive Note : Final rept.,

Corporate Author : MICHIGAN COLL OF OSTEOPATHIC MEDICINE PONTIAC*

Personal Author(s) : Houlihan,Rodney T.

Report Date : 31 DEC 1972

Pagination or Media Count : 9

Abstract : The involvement of epinephrine oxidation and indole production during acute oxygen poisoning was investigated. Cyclic oxidation of epinephrine has been verified. Adrenalectomy, which protects animals from oxygen toxicity, inhibits indole production. Enzyme activity is significantly increased during exposure to high pressure oxygen. There are species differences with respect to lung changes following seizures induced by hyperbaric oxygen. (Author Modified Abstract)

Descriptors :   (*OXYGEN, *SYMPATHOMIMETIC AGENTS), (*HIGH PRESSURE, OXYGEN), AMINES, METABOLISM, TOXICITY, ENZYMES, EPINEPHRINE, INDOLES, OXIDATION

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE